2026
11 篇文章把兩階段訓練拿掉之後:SimpleDesign 對蛋白質設計流程的意義
Apple 的 SimpleDesign 直接在資料空間訓練序列與結構共同設計模型,挑戰先訓練 autoencoder 的兩階段慣例。
閱讀文章 ↗把生物序列當搜尋空間:Codex 與 ChatGPT 如何縮短抗菌分子前期探索
César de la Fuente 的實驗室用深度學習模型加上 Codex、ChatGPT,把抗菌候選分子的前期搜尋從數年壓縮到數小時。
閱讀文章 ↗AlphaGenome Atlas:把 90 億個 DNA 變異變成可查詢的預測地圖
Google DeepMind 推出 AlphaGenome Atlas,涵蓋人類基因組中所有 90 億個單核苷酸變異的分子效應預測,並提供 AVI 分數與特徵歸因,協助研究人員快速排序與解讀變異。本文從產品建造者角度,解析這份 1PB 資料集的設計、應用與限制。
閱讀文章 ↗Triomics 拿下 2,200 萬美元 B 輪:腫瘤科專用 AI 讀上千頁病歷
Triomics 獲 Battery Ventures 領投 2,200 萬美元 B 輪。其腫瘤科專用 AI 以 OncoLLM 讀取上千頁病歷,做試驗匹配、訪前整理與登記抽象,客戶含 MSKCC 與耶魯癌症中心,ARR 年增十倍。
閱讀文章 ↗10x Science:用質譜 AI 代理打通藥物開發的下游瓶頸
2026 年 4 月,出身諾獎得主 Bertozzi 實驗室的團隊創辦 10x Science,募得 480 萬美元種子輪,用質譜數據訓練 AI 代理,解決 AI 生成候選藥物之後的表徵分析瓶頸。本文看它的技術路線與製藥 SaaS 商業模式。
閱讀文章 ↗牛津 AI 從 CT 影像預測心衰竭:提前五年、風險最高達 20 倍
牛津大學 Radcliffe 醫學系團隊以逾 7 萬筆匿名 CT 掃描訓練 AI,透過心臟周圍脂肪的紋理變化預測心衰竭,最早可提前五年、準確率約 86%,最高風險組發病機率約為常人 20 倍。本文解析這項技術與臨床部署的距離。
閱讀文章 ↗Anthropic 以 4 億美元收購 Coefficient Bio,跨入 AI 製藥再進一步
2026 年 4 月初,Anthropic 以約 4 億美元全股票收購成立八個月的生技 AI 新創 Coefficient Bio,九人團隊多來自 Genentech。本文解析交易結構、兩位創辦人背景,與藥廠人才流向 AI 公司的產業變化。
閱讀文章 ↗禮來 LillyPod 啟用:1,016 顆 NVIDIA GPU 的製藥 AI 工廠
禮來與 NVIDIA 合作打造的 LillyPod 正式上線:1,016 顆 Blackwell Ultra GPU、超過 9,000 petaflops,是製藥業最強大的 AI 超級電腦,用於基因體學與藥物設計,並支撐 TuneLab 聯邦學習。但禮來 AI 長提醒:瓶頸在生物學,不在算力。
閱讀文章 ↗從 OpenAI 辦公室到禮來合約:Chai Discovery 的 AI 製藥突圍
2024 年成立、從 OpenAI 辦公室起家的 Chai Discovery,以 13 億美元估值完成 1.3 億美元 B 輪募資,並與禮來 TuneLab 及 argenx 展開抗體設計合作。本文拆解這家 AI 製藥新創的技術定位、資本路徑與臨床時程考驗。
閱讀文章 ↗Anthropic 推出 Claude for Healthcare:HIPAA 就緒的醫療與生命科學佈局
2026 年 1 月 11 日,Anthropic 發表 Claude for Healthcare:HIPAA 就緒的連接器、Agent Skills 與個人健康資料工具,並將生命科學版圖從臨床前推進到試驗與法規。本文拆解產品細節、藥廠實績與合規邊界。
閱讀文章 ↗Insilico Medicine 港交所掛牌:AI 製藥首度叩關港股主板
2025 年 12 月 30 日,Insilico Medicine 以代號 3696.HK 登陸港交所主板,募資 22.77 億港元,成為當年香港最大生技 IPO,也是首家在港主板上市的 AI 生物科技公司。公開發售超購約 1,427 倍,背後是 AI 製藥從概念走向商業化的十年長跑。
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2026
12 ARTICLESOne Training Stage for Protein Design: What Dropping the Latent Space Changes
Apple's SimpleDesign skips the usual two-stage latent pipeline and trains sequence and structure together in data space.
READ POST ↗Codex and ChatGPT in an Antimicrobial Lab: What the Workflow Actually Looks Like
A bioengineer's lab uses Codex and ChatGPT to bridge biology, chemistry, and code in antimicrobial discovery.
READ POST ↗AlphaGenome Atlas: A Precomputed Map of 9 Billion DNA Variants Changes How We Prioritize Genetic Research
Google DeepMind's AlphaGenome Atlas turns variant interpretation from a per-variant query into a precomputed, rankable dataset.
READ POST ↗Anthropic's rare disease research grants: $50,000 in Claude credits and a two-track design
Anthropic's AI for Science call targets rare genetic diseases with up to $50,000 in Claude credits across two tracks: Monarch's infrastructure, three grantees, and the limits Anthropic drew.
READ POST ↗Triomics Raises $22M Series B for Oncology-Specific AI
Triomics raised a $22M Series B led by Battery Ventures. Its oncology LLM reads thousand-page records for trial matching, pre-charting, and registry abstraction.
READ POST ↗10x Science Points AI Agents at Drug Pipeline Bottleneck
10x Science raised a $4.8M seed to aim AI agents at mass spectrometry — the bottleneck downstream of AI drug candidate generation. Founded by Bertozzi lab alumni.
READ POST ↗Oxford AI Predicts Heart Failure Five Years From CT
Oxford medicine researchers trained an AI on 70,000+ CT scans to flag heart failure risk five years early at 86% accuracy; top-risk patients are 20x more likely to develop it.
READ POST ↗Anthropic Buys Coefficient Bio in $400M Drug-Discovery Push
Anthropic's ~$400M all-stock deal for eight-month-old Coefficient Bio, an ex-Genentech team of nine, moves Claude deeper into drug R&D — deal terms, founders, sector impact.
READ POST ↗LillyPod Goes Live: Pharma's Most Powerful AI Supercomputer
LillyPod is live: 1,016 Blackwell Ultra GPUs, 9,000+ petaflops — pharma's most powerful AI supercomputer, built with NVIDIA for genomics and drug design. Biology, not compute, remains the bottleneck.
READ POST ↗Chai Discovery: From OpenAI's Offices to an Eli Lilly Deal
Founded in 2024 in OpenAI's offices, Chai Discovery closed a $130M Series B at a $1.3B valuation and landed Eli Lilly's TuneLab and argenx for AI antibody design — now the clinical clock is running.
READ POST ↗Anthropic Launches HIPAA-Ready Claude for Healthcare
On January 11, 2026, Anthropic launched Claude for Healthcare: HIPAA-ready connectors, agent skills, and opt-in personal health tools, plus a life sciences push into trials.
READ POST ↗Insilico Lists in Hong Kong: AI Drug Discovery Goes Public
Insilico Medicine listed on HKEX's Main Board on Dec 30, 2025 (3696.HK), raising HK$2.277B in the year's largest HK biotech IPO, with retail oversubscription of 1,427x — a first for AI biotech.
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